Wednesday, October 16, 2019
Partition after Civil Wars Research Paper Example | Topics and Well Written Essays - 1500 words
Partition after Civil Wars - Research Paper Example The resulting settlements of the issue after the bloody civil wars can often result into further bloodshed. Breakout of the State as a result of the ethnic issues therefore can put different ethnicities against each other and make the overall experiment worse because of the ease with which methods like ethnic cleansing can be adapted. What is also significant to understand that author has critically argued that in order to avoid ethnic civil wars, it is important that partition should be considered as one of the viable policy alternative. This argument is based on the assumptions that the ethnic conflicts have almost similar dynamics thus making it difficult to put back the multi-ethnic state in same state as before the war. Independent and Dependent Variables A closer analysis of the article would suggest that author has attempted to create link between the ethnic conflicts and civil wars with the partition. As such the dependent variable is the partition of the geographical areas w hereas the achievement of peace and lack of conflict as a result of the ethnic conflict as an independent variable. ... Case studies are often based upon an in-depth analysis of certain events, groups or individuals and as such can provide a comprehensive overview of subjects under review. Author has provided comprehensive details of the different ethnic conflicts which took place and the results of their settlement. Author has also used survey of the existing literature to present a theoretical analysis of the overall context of the ethnic conflicts and their solutions. Survey of existing literature also offers a valid theoretical platform based on which author can actually build the theoretical foundations for the research undertaken. By citing various examples from history author has actually been successful in providing a comprehensive overview of how the different negotiating settlements failed due to non-partition based solutions to the problem of ethnic conflicts. Conclusion This article is comprehensive in the sense that it has offered a very comprehensive overview of the historical accounts o f the different ethical and cultural conflicts. The overall theoretical foundations are set to discuss various approaches forwarded to resolve the multi-ethnic conflicts and how they failed to achieve the desired results. Author has adapted case study approach under which an overview of the different conflicts and their settlements. The overall conclusion of the article is that the partition can be one of the feasible policy alternatives to solve the ethnic conflicts and avoid civil wars. Are you convinced? Why? Though partition can be one of the key policy alternatives however, to get an overall acceptability of the same may remain one of the key challenges to such policy alternatives. In case such as Palestine and Israel where a separate State has been created for
Tuesday, October 15, 2019
Cost and Benefits of Internal Recruitment for ACE Media Group Essay
Cost and Benefits of Internal Recruitment for ACE Media Group - Essay Example ACE Media Group will also save training and recruitment costs as the employee recruited will not need intensive training to perform his or her duties as a project lead in Malaysia. The director will only need to acclimatize to the foreign business environment but will not struggle to acquaint himself with the policies of the firm. The approach is also beneficial to the organization as it is much easier. The HR recruitment team will have access to sufficient information on potential candidates from its various branches across the world such as Sydney, UK, France Singapore and China. The availability of the information pool will make the selection process easier. In addition, internal recruitment will also facilitate succession planning. ACE Media group will incur several costs associated with internal recruitment. First, they would bear the opportunity costs linked to recruiting old talent who lack new perspectives acquired from outside the organization. Being that ACE Media Group is a big business, it is possible that internal politics will arise among interests groups, and this may jeopardize the unity of workers. Internal recruitment may not help in turning the company around as the recruited employee will tend to stick to the usual strategies and stale ideas due to inbreeding within the firm. External recruitment may bring to the company a new employee possibly a Malaysian who may not facilitate quick settlement in the foreign market due to local politics and prejudice.
Criminals are made, not born. Critically discuss this statement Essay
Criminals are made, not born. Critically discuss this statement - Essay Example In this paper will be discussed why a person would commit a crime, and why a person would need both a sociological determinism and a biological determinism. Biological determinism would include an extra Y chromosome. The normal man is born with only XY chromosomes. Some men are born with XYY chromosomes. Having an XYY chromosome means a man is more aggressive, when a man is more aggressive a man may sometimes commit a crime. Aggressive men commit aggressive crimes. Men with an extra Y chromosome will most often commit crimes like rape, and other violent crimes. This theory is generally accepted. However, it has been determined through conclusive evidence that some men who commit violently, and aggressive crimes like rape do not necessarily have an extra Y chromosome. So if men who commit violent crimes do not all have an extra Y chromosome there must be other determinants in what makes people commit a violent crime. There are also women who commit crime. Women do not have an extra Y chromosome. Some women also commit violent crimes. Therefore, one might need to look at the Chicago school theory. The Chicago school theory of why a person commits crime is one that focuses on a person societal environment. This theory focuses on people committing crime because of the environment they live in. The Chicago school adopts many other theories like the strain theory. The strain theory is a theory that says people commit crimes because these criminals are under strain. The strain can come from a number of sources. Strain can come from breaking up with oneââ¬â¢s boyfriend, or girlfriend. Financial strain can come from the environment in which one lives. This is how the strain theory incorporates into the Chicago school theory. The Chicago school theory states that one would commit a crime because of financial strain induced by the environment one lives. Is this possible? Do people commit white-collar crimes, financial crimes, violent crime, and other blue collar crimes due to strain? The labeling theory is one of the most generally accepted theories in criminology. The labeling theory states that one develops deviant behavior because one is often told that one is a juvenile delinquent. The labeling theory states that once someone has a label, it is difficult to get rid of the label. One can also develop deviant behavior because of other labeling. Labeling theory states that many develop deviant behavior, because these people are labeled lazy and delinquent. Many who have been labeled as deviant, and delinquent will often seek the advice, and guidance from other deviant, and delinquent people. Some of these deviant, and delinquent people will be those of gang members. One might think someone with a label of deviant, and delinquent may want to shed that label. However, it appears many do not shed the label. Many are not interested in shedding the label. Many will conform to what society expects them to conform to. When one thinks that someone is no t interested in shedding the label that has them placed upon them one might think that would be impossible. Many people with a label have a difficult time finding a job. Many who are labeled will often commit further crime to meet financial needs. In committing further crime to meet financial needs cuts of a label one cannot find legitimate work. When one cannot get find legitimate
Monday, October 14, 2019
Brain Injury Essay Example for Free
Brain Injury Essay Describe the possible signs, symptoms, indicators or behaviours that may cause concern in the context of safeguarding. A Person may abuse by either inflicting harm or failing to prevent the harm occurring. Some of the behaviours indicating possible concern with regards to safeguarding children are: Physical abuse: such as bruises to parts of the body, fingertip bruising (grasp mark), bruises of different ages in the same place. Outline bruises (hand prints, belts or shoes). It could be burns, bites and scars and fractures, poisoning or drowning. Physical harm could also be when a parent/carer makes up medical symptoms or deliberately causes illness in a child/young person Neglect: such as the child/young person being undernourished, having dirty skin and hair, dirty or soiled clothing, inappropriate clothing for the weather, hunger and stealing food, always being tired, being withdrawn, being left unsupervised inappropriately and not being given any medical care. Neglect may also occur in pregnancy, if the mother is taking illegal drugs or excessive alcohol. Sexual: abuse such as recurrent urinary infections, genital and rectal itching and soreness, inappropriate behaviour regarding age and ability, inappropriate level of sexual knowledge, and sexual abusive behaviour toward others, lack of trust, regression, become isolated and withdrawn. Emotional abuse such as low self-esteem, attention seeking behaviour, nervous behaviour, continual rocking, hair twisting, delayed development, and self harming. Describe the actions to take if a child or young person alleges harm or abuse in line with policies and procedures of own setting If a child or young person alleges they have been harmed or abused I would listen carefully to them and stay calm. I would not show repulsion or shock. I would show that I believed the child and would reassure them. I would give them time to talk and wouldnââ¬â¢t hurry them. I would take notes ââ¬Ëin the momentââ¬â¢ and record facts correctly. I would not put words into their mouths or ask closed questions I.E: ââ¬Å"What happened, rather than did they hit you?â⬠I would let them talk as much as they wanted to and not interrupt them. I would not promise the child/young person that I would not tell anyone and explain that I may have to tell the appropriate people. The degree of confidentiality will be governed by the need to protect the child/young person. Depending on the situation I would either call my supervisor or manager to discuss there and then, or go straight back to the office and discuss face to face with my supervisor or manager. I would then type up the report whilst it was fresh in my mind. If the child was not safe or at risk of harm and had to be removed from the home I would wait until the appropriate people attended. Depending on the severity of the abuse, I may call the police, child protection and health professionals. We have a duty of care by law to report any safeguarding issues/concerns with the appropriate people. We should NOT confront an alleged abuser.
Development of Surface Plasmon Resonance (SPR) Sensor
Development of Surface Plasmon Resonance (SPR) Sensor INTRODUCTION CHAPTER-1 INTRODUCTION The physical processes involved in surface plasmon resonance (SPR) phenomena were first reported by R.M. Wood in 1902 [1]. In this work, Wood observed a repeated pattern of dark and bright light bands in the reflected light, when he irradiated polarized light on a mirror with a diffraction grating on its surface. The physical interpretation of SPR mechanism was first initiated by the British physicist Lord Rayleigh [2], and further refined by Fano [3], but its satisfactory explanation was not available until 1968, when Otto [4] and in the same year Kretschmann and Raether [5] reported the excitation of surface plasmons on the metal/dielectric interface. Its first use in a real-time analysis of a biological system was demonstrated in 1990s by Karlsson et al. [6]. Since then, The SPR has become a crucial optical sensing technique in the areas of biology, microbiology, biochemistry, and medical sciences because of its noninvasive nature [7]. The commercially available SPR based devices are not so cost-effective and require consumable sensor chips demanding certain specifications of size, thickness, effective sensing area and so on. For example, The Biacore (acquired by General Electric Healthcare in 2006), a life science products company, are providing a variety of models of SPR-based instruments (a typical cost of $120,000ââ¬â$250,000) that exhibit compatibility only with expensive Biacore accessories. Moreover, the associated high operational cost inhibits introduction of SPR technique into laboratory classes at the undergraduate or postgraduate level. In addition to that, the commercial SPR instrument is not a good teaching tool because all the components, of the apparatus, are enclosed, thus preventing the students from visualizing the details of the SPR instrumentation. The primary motivation behind the present project work is to develop a low-cost SPR based multipurpose optical sensor especially intended for undergraduate and postgraduate education and Research. The proposed homemade SPR sensor is supposed to be cost-effective, and whose all components would be accessible for visualization and manipulations in future. The presented design not only allows its integration with various other mechanical and electronic add-ons, but also could prove to be an ingenious teaching tool for the students to understand and appreciate the modern instrumentation. In addition, once developed, this instrument could also serve the Research purposes of general chemistry, biochemistry, physical chemistry, Nanotechnology and Material Sciences. For this purpose it was necessary to arrange low cost experimental components but keeping in mind that these components work well to satisfy our purpose. It took a long time first to decide the components, and then taking overviews from various places regarding the type of component available and the price of that particular component. After comparing and analyzing the need and price of whole set-up the components were arranged from different market places. After arranging the components it was necessary to prepare the experimental set-up in a well mannered way to fulfill our purposes. Again it took a long time to arrange them in a dark room (as we were working on light and its intensity measurement) as to get a well observable result. The most difficult and time consuming task was to produce a thin metallic film on the glass slide of a specific thickness to get a better result. Metallic film was of gold and the coating unit was a magnetron sputtering gold coater available in the department of the institute. Initially it was a difficult task to coat the glass slide of specific thickness, for which we coated various glass slides with different thicknesses using variable coating time of the coater. Then we did the experiments with that thickness but didnââ¬â¢t get the results. Then glass slides were again coated to increase the gold film thickness. This process was repeated various times and at last we were succeeded to produce the res ults from the glass slides of different thicknesses. In this dissertation work, we first introduce the principle of Surface Plasmon Resonance and other associated phenomena. Following the introduction part, we describe some literature reviews in next section of report. We further describe the details of the crucial components that would be used in the development of SPR based Sensor or can be termed as the Experimental Set-up for the Surface Plasmon Resonance phenomenon. The very next section contains the soul of the whole report or the Results, mentioned as results and discussion. We finally conclude the report by enumerating the work done so far, the future course of work followed by the References that have been used for the literature survey. SURFACE PLASMON RESONANCE- Principle: SURFACE PLASMON RESONANCE(SPR): The resonant oscillation of conduction electrons, at the interface between a metal and dielectric, stimulated at the optical frequencies is called the SURFACE PLASMON RESONANCE (SPR). Thisà resonanceà condition is satisfied once the incidentà photon frequency matches with the natural frequency of surface electrons, which are oscillating under the action of restoring force of positive nuclei of the metallic atoms. The resonance phenomena has been shown to have many applications such as in Gas detection and immune-sensing [8,9], efficiency enhancement of Solar Cells [10], and Magneto-Optical based imaging etc. [11,12]. Figure 1 shows a typical surface Plasmon resonance set-up which consists of a light source, prism, gold film, and a detector. Figure 1: Schematic diagram of a surface Plasmon resonance set-up. Here n1 and n2 show the refractive indexes of prism and air respectively. SURFACE PLASMON POLARITONS (SPP) wave -The surfaceà electromagnetic waves, propagating along theà metal/dielectricà or metal/vacuum interface, is known as SURFACE PLASMON POLARITONS (SPP) wave. As the SPP wave is propagating along the boundary of the metal and the external medium (air or dielectric), the aforesaid resonant oscillations become extremely sensitive to any change occurring at the boundary, for instance the adsorption of molecules to the metal surface or change in refractive index at the metal-dielectric surface. Thus the sensitivity associated with metal ââ¬â dielectric interface can be exploited to obtain a non-destructive and cost effective multipurpose sensor for detection of Chemical and Biological species. According to different literature [9,12], the sensing properties has been quite useful for monitoring food quality, safety analysis, medical diagnostics and environmental changes etc. A typical SPR sensor consists of a dispersive element, such as prism or a plane reflection grating, coated with a metallic layer (Gold) and a dielectric layer (usually polymers or bio molecule layers). The Kretschmann configuration, as shown in Figure 2, is often used in most of the SPR sensor applications, where a metal (typically silver or gold) film is placed at the interface of two dielectric media. The medium 1 with higher refractive index (n1) is a prism and the medium 2 with lower refractive index (n2) can be the air or the dielectric of interest. A collimated p-polarized light beam, entering from the glass side undergoes a total internal reflection and interacts with the metallic layer at the critical angel of incidence (as shown in Figure 2). The surface plasmons (SP), at the metallic surface, are excited at the resonance optical frequency resulting in absorption of a part of incident light energy and hence leading to a sudden drop in Reflectance at a specific angle à ¯Ã à ±0 adjacent to the critical angle à ¯Ã à ±C. The resonance condition of the SPs is sensitive to any change in the refractive index of the metal-dielectric interface and leads to shift of à ¯Ã à ±0 to a new angle à ¯Ã à ±1 (Figure 2). The change in the intensity of reflected or diffracted light or its wavelength or angular spectrum can be monitored using a charge coupled device arrays or photodiode arrays, for different sensing purposes [13-16]. Figure 2: Diagram representing the Surface Plasmon Resonance mechanism. TOTAL INTERNAL REFLECTION AND EVANESCENT WAVES: When the light travels from the higher refractive index medium 1 (glass) to the lower refractive index medium 2 (air or dielectric), the total internal reflection (TIR) takes place within medium 1 for the incident angles à ¸ greater than the critical angle à ¸C, satisfying the Snellââ¬â¢s relation Sin (à ¸C) = n2/n1. The Evanescent waves, a near-field wave, are produced in the lower refractive index medium 2 (air or dielectric) under the TIR condition. As the meaning of Evanescent is tending to vanish, the amplitude of evanescent waves decays exponentially with the distance from the point of incidence, to the interface of the media 1 and 2. When a nonmagnetic gold film with a suitable thickness is sandwiched between the media 1 and 2, the amplitude of evanescent wave is enhanced, penetrating in the gold film and also existing simultaneously in the medium 2. Using the well known Fresnelââ¬â¢s relations, magnitude of the parallel wave vector of the evanescent wave, , is expres sed as; (1) where à » is the wavelength of the incident light, n1 is the refractive index of the higher refractive index medium 1, and à ¸ is the angle of incidence. Figure 3: Schematic diagram showing a layer system of surface Plasmon resonance where kevan and ksp are wave vectors given in equations. SURFACE PLASMONS: Surface plasmons (quanta of plasma), are the surface electromagnetic wave travelling along the limited region of metalââ¬âdielectric interface. The magnitude of the wave vector of the surface plasmon is connected to the dielectric constants of medium 2 (n2) and the gold film (ng). For most of the non absorbing materials, the magnetic permeability is very close to unity at optical frequencies. Hence, the dielectric constant for such materials becomes equal to the square of the refractive index i.e. à µ = n2. Here à µ is the dielectric constant and n is the refractive index. As a result, can be obtained from n2 and ng using the following relation; (2) where n2 is the refractive index of medium 2 adjacent to the interface and ng is the refractive index of the gold film. SURFACE PLASMON RESONANCE: In presence of the evanescent wave, the surface plasmon can be excited leading to the phenomenon of surface plasmon resonance (SPR). In this situation, the intensity of the reflected light, from the metal-dielectric interface, decreases abruptly (as shown in Figure 1). In this process the energy of evanescent wave is conserved and the energy of the excited surface plasmon is coupled to phonons or photons generation at the interface. Hence, the energy conservation requires that equals to . Thus, using eqs 1 and 2 the angle , at which SPR occurs, can be determined by below relation, (3) Here, the incident angle at which the minimum reflectivity is observed is called the SPR angle. The angle has been found to be slightly larger than the critical angle . It is clear from above expression that the angle is linked to n2 if n1 and ng are kept fixed. Hence, even a slight change in the refractive index of interfacial region is reflected in a significant change in the angle . For instance, the phenomena of adsorption and desorption of any gas, on the gold surface, changes the refractive index of media 2 near the metalââ¬âdielectric interface leading to change in the . Therefore, the monitoring the change in the angle can be used, as a technique, to study and analyze the adsorptionââ¬â desorption or associationââ¬âdissociation phenomena taking place on the gold surface. The refractive index, in the interfacial regime, changes with the mass and density of foreign species attached to the gold film surface. As a consequence, monitoring the change in the SPR angl e provides information about mass and density change on the gold surface, effectively within 200 nm from a metal surface. As mentioned above the surface Plasmon resonance will occur when, Also from the above discussion we know that the is a function of three parameters. The wavelength of incident light. The refractive index of medium 1 or glass prism. Angle of incidence of the incident light falling on the metal-dielectric junction. And also is a function of three parameters, The wavelength of incident light. The refractive index of metallic thin film. The refractive index of the second medium or the air. So we get five different parameters which can be used as varying parameters to get the optimum condition of Surface Plasmon Resonance which are, The wavelength of incident light, The refractive index of medium 1, The refractive index of medium 2, The refractive index of metallic film, and The angle of incidence of incident light. In wavelength interrogation Surface Plasmon Resonance device, wavelength of incident light is varied whereas the other parameters including incident angle, refractive indexes of medium 1, medium 2 and medium 3 are kept constant during the whole experiment. In this case there is a variation in the intensity of reflected light with variation in wavelength of incident light as shown in figure 4. Figure 4: Shows relationship between absorbance of reflected light and the wavelength of incident light. In angle interrogation Surface Plasmon Resonance device, incident angle of light is varied whereas the other parameters including wavelength of incident light, refractive indexes of medium 1, medium 2 and medium 3 are kept constant during the whole experiment. In this case there is a variation in the intensity of reflected light with variation in angle of incident light as shown in figure 5. Figure 5: Diagram indicating the relationship between intensity of reflected light and incident angle. The other type of interrogation device is refractive index interrogation Surface Plasmon Resonance device in which refractive index of any medium is varied which is a tough task and that is why used in very rare cases. Other parameters are kept constant in this type of interrogation system including wavelength of incident light as well as the incident angle of the light. In this case there is a variation in the intensity of reflected light with variation in refractive index of the medium taken in consideration as shown in figure 6. The one other and most complicated interrogation system is phase interrogation Surface Plasmon resonance device in which phase of the reflected light provides the information about the metal dielectric interface. Very less work has been done in this field and is a good topic to work on in future as angle dependent reflectance measurement and other methods discussed above are limited for detecting low weight molecules on the metal dielectric surface. Figure 6: shows relationship between intensity of reflected light and refractive index of the medium with three different gold film thicknesses. Now refractive indexes of medium 1(glass), medium 2(air) and the gold metallic thin film cannot be varied simply during a running experiment. So we have only two parameters which can be used as variable parameters, the wavelength of the incident light and the angle of incidence of that light falling on the set-up. In our work, we have used the later one for our purpose which is angle of incidence of the incident light on the metal dielectric interface, and making the wavelength of the incident light constant near about 650 nm which means we have used a red laser as a source of the light for our experimental set-up. Angle of incidence can be varied either be rotating the light source around the prism or by rotating the prism on its axis and making light source stationary. We are rotating the prism which is mounted on a rotational prism table to vary angle of incidence.
Sunday, October 13, 2019
Intravascular papillary endothelial hyperplasia
Intravascular papillary endothelial hyperplasia Intravascular papillary endothelial hyperplasia, regarding a case INTRODUCTION Intravascular papillary endothelial hyperplasia (IPEH) was first described as a malignant lesion by Pierre Masson in 1923(1), warning his histological similarity to angiosarcoma. Later, Henschen(2) described an intravascular endothelial proliferation that he interpreted like a reagent process due to inflammation and stasis vascular. We present a case of a patient diagnosed with intravascular papillary endothelial hyperplasia in renal vein. CASE REPORT 61 years old male referred to our department with symptoms compatible with right renal colic. He has previous history of hypertension, obstructive sleep apnea syndrome and benign prostatic hyperplasia with alpha-blocker therapy. The patient relates intense pain in the right flank, sometimes radiating to ipsilateral inguinal region. On physical examination revealed pain with percussion in the right flank. Blood and urine analysis, abdominal radiography and ultrasound are requested, all of them normal. Due to the persistence of symptoms, CT scan with contrast was requested (Fig. 1), in which a solid mass of 3.5 x 3 x 4 cm, lobulated and with heterogeneous necrotic center located at the right renal hilum infiltrates renal vein is seen . This mass is adjacent to lower portion of adrenal gland, kidney, and posterior portion of the duodenum, not clearly identifying dependency. To try to understand the dependence of this mass MRI is requested (Fig. 2), which describes hypointense on T1 and hyperintense on T2 tumor, with probable adrenal gland dependence. Suspecting adrenal injury, hormonal and metabolic study is carried on in blood and urine of 24 hours, all was normal. Scintigraphy was also performed with MIBG finding no enhancing lesions. Given previous findings, and the likelihood of adrenal malignancy (nonfunctional), surgery is decided. By a subcostal laparotomy, a tumor about 4 cm, firmly adhered to the renal hilum is observed. Right radical nephrectomy is performed due to impossibility the tumor excision alone. Postoperative course without incidences and the patient was discharged on the fourth day. Microscopic examination of the surgical specimen revealed kidney and adrenal gland unaltered. Near of the renal hilum and, at least partially, contained within a dilated vein, thrombosis and endothelial reactive area proliferation (capillary and papillary), compatible with papillary endothelial hyperplasia intravascular (Fig 3). Currently the patient is reviewed every six months, with analytical tests and CT normal. DISCUSSION Enzinger and Clearkin(3) suggested several morphological features that served in the differential diagnosis between IPEH and angiosarcoma, including intraluminal location of the lesion, absence of necrotic tissue and presence of thrombotic material, and proposed the intravascular papillary endothelial hyperplasia term. The etiology of IPEH is still unknown. Trauma has been proposed as the main etiological factor, but the traumatic history is exceptional. Several authors agree with the view of Clearkin and Salyer who believe it is due to an alteration in the thrombosis process, consisting of an unusual and peculiar way of organizing thrombus.( 3,6 ) IPEH can occur at any age, more frequently in female. Most of the cases are localized to skin vessels, in head and neck, where they appear as small hard mass of bluish red coloration to the skin. Although there have also been less frequent locations as jejunum, central nervous system, liver, and lungs (4,5). Three forms have been described: Primary, on dilated vascular lakes; secondary or mixed, with preexisting vascular lesion as hemangioma , arteriovenous malformations or pyogenic granuloma; and the third and less frequent, extravascular, resulting in a hematoma (7). The finding of IPEH in the renal vein is rare, there are very few cases reflected in the literature. The symptoms are variable, ranging from an incidental finding, asymptomatic, to colic pain and hematuria. In imaging, with the CT scan with contrast we can find a solid lesion with heterogeneous contrast enhancement, and in MRI a lesion hypointense on T1 and hyperintense on T2 , which does not exclude malignancy(8, 9). In a case reported(10), preoperative diagnosis was performed with excision of the lesion and kidney preservation. But in most cases, it was impossible to rule out malignancy, and the radical surgery is usual, either for technic impossibility by proximity to the renal vessels, or the suspicion of malignancy. No metastases or malignant degeneration has been reported. Preoperative diagnosis of IPEH is difficult as there are no characteristic symptoms or an imaging test that allows adequate differential diagnosis. There are several neoplastic and non-neoplastic lesions that can be found in the renal hilum. Among them: renal carcinoma, angiomyolipoma , schwannoma , myelolipoma , hemangiopericytoma , lymphoma, cysts, Castleman disease or lipomas. Therefore, this condition, although rare, must fall within the diagnostic possibilities, especially if their dependency or proximity to vessels is detected. CONFLICT OF INTEREST The authors declare no conflict of interest REFERENCES Masson P. Hemangioendothelioma vegetant intra-vasculaire. Bull Soc Anat Paris 1923;93:517ââ¬â23. Henschen F. Là ´endovasculite proliferante thrombopoietique dans la lesion vasculaire locale. Ann anat Pathol 1932;9:113-21. Clearkin KP, Enzinger FM. Intravascular papillary endotelial hiperplasia. ARch Pathol Lab MEd 1976;10:441-4. Johraku A, Miyanaga N, Sekido N, et al. A case of Intravascular Papillary Endothelial Hyperplasia Arising from Renal sinus.Jpn J clin Oncol 1997; 27(6) 433-36. Pelosi G, Sonzogni A, VIale G. Intravascular Papillary Endothelial Hyperplasia of the renal vein. Int J Surg Pathol 19(4) 518-20 Salyer WR, Salyer DC. Intravascular angiomatosis: development and distinction from agniosarcoma. Cancer. 1975; 36: 995-1001 Hashimoto H, Daimaru Y, Enjoji M. Intravascular papillary endothelial hyperplasia. A clinicopathological study of 91 cases. AM J Dermatopathol. 1983; 5:539-46 Kuo T, Sayers CP, Rosai J. Massonà ´s `Vegetant intravascular hemangioendotheliomaà ´: a lesion often mistaken for angiosarcoma. Cancer 1976; 38: 1227-36. Van den bogaert S, Boel K, Van Poppel H, et al. Massonà ´s tumour of the kidney. Cancer Imaging. 2002; 2: 116-9. Akhtar M, Aslam MAL-Mana H, et al. Intravascular Papillary endothelial Hyperpasia of Renal Vein. Arch Pathol Lab med. 2005;129: 516-520 LEGENDS TO FIGURES Fig.1CT: heterogeneous mass with necrotic core located in the right renal hilum. Fig. 2 T1-weighted MR image: hypointense mass on the right renal hilum. Fig. 3 Histological specimen. Close to the renal vascular pole and partially including a dilated vein, an intravascular thrombus and a reactive endothelial proliferation zone (capillary and papillaroid) are observed. Fig. 4 Greater magnification of the previous image, which can be seen proliferation of papillary structures that tend to anastomose that are lined by a row of endothelial cells, centered on an axis of collagen and fibrin. No images of necrosis, atypia or mitosis (not characteristic of malignancy) were observed.
The War on Drugs is Failing Essay -- George Bushs War on Drugs
The War on Drugs is Failing ââ¬Å"Prohibition will work great injury to the cause of temperanceâ⬠¦ for it goes beyond the bounds of reason in that it attempts to control a manââ¬â¢s appetite by legislation and make a crime out of things that are not a crime. A prohibition law strikes a blow at the very principle upon which our government was foundedâ⬠Abraham Lincoln On January 16, 1920 the Eighteenth Amendment was ratified by thirty-six states and became part of the Constitution. The intention of this new amendment was to lower alcohol consumption by Americans. At the time each American consumed on average thirty gallons of alcohol a year.[1] This new amendment took away the license to do business from the brewers, distillers, and the wholesale and retail sellers of alcoholic beverages. Alcohol consumption did taper off somewhat at the beginning of prohibition only to slowly rise back to pre-prohibition levels shortly before the end of the movement which took place on December 5,1933. Not only was the goal of prohibition never achieved, but it raised organized crime to levels of power unimaginable before and seriously disrupted both the legitimacy and revenue of the government. Just as Prohibition incited many unsavory activities, so has the War on Drugs. The easiest way to show the connection between these to movements is an excerpt from an article pertaining to Prohibition in America during the 1920ââ¬â¢s: Bootleggers ran wild. Professional robberies began as soon as Prohibition did. Territories were divided by groups of organized crime that became the scum known as the Mafia. The territories were decided by violence and death, both against each other, as well as those in the public who may/may not have been innoce... ...equipped with state of the art learning tools. Teachers will receive pay raises. Students will be in an environment conducive to learning. Not to mention violence in schools will diminish drastically. Public schools across America would phase out drug addicts by teaching drug awareness, tolerance and moderation. It is quite clear that the War on Drugs is failing. A drug free country would be ideal. So would an alcohol-free country, a pollution-free country, and most likely a fast food-free country. None of these things will happen, so we have to make the best out of the situation as it is presented. The only practical method of dealing with this problem is the legalization of drugs. The government should take advantage of the money drug revenues will generate to supply the youth of America with the knowledge to make the right choice.
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